失眠多為情志所(suo)傷，久病體(ti)虛(xu)(xu)，飲食不節，勞逸失度等(deng)引(yin)起陰陽失調，陽不人陰而發。病位(wei)主要在心(xin)(xin)(xin)，涉及(ji)肝、膽(dan)、脾(pi)(pi)、胃(wei)、腎。病性有虛(xu)(xu)實之分。其(qi)實證(zheng)者(zhe)，多因心(xin)(xin)(xin)火偏亢，肝郁化火，痰熱內擾(rao)，胃(wei)氣(qi)(qi)(qi)失和(he)，引(yin)起心(xin)(xin)(xin)神(shen)不安所(suo)致(zhi)，治當清(qing)心(xin)(xin)(xin)瀉火，清(qing)肝瀉火，清(qing)化痰熱，和(he)中(zhong)導滯，佐以安神(shen)寧心(xin)(xin)(xin)。其(qi)虛(xu)(xu)證(zheng)者(zhe)，多由(you)陰虛(xu)(xu)火旺，心(xin)(xin)(xin)脾(pi)(pi)兩虛(xu)(xu)，心(xin)(xin)(xin)膽(dan)氣(qi)(qi)(qi)虛(xu)(xu)引(yin)起心(xin)(xin)(xin)神(shen)失養所(suo)致(zhi)，治當滋陰降火，補益心(xin)(xin)(xin)脾(pi)(pi)，益氣(qi)(qi)(qi)鎮驚，佐以養心(xin)(xin)(xin)安神(shen)。

    牛黃(huang)(huang)清(qing)(qing)(qing)(qing)(qing)熱(re)(re)(re)解(jie)毒，化(hua)痰(tan)(tan)定(ding)驚(jing)，珍珠鎮心安(an)神，養(yang)陰(yin)熄風，清(qing)(qing)(qing)(qing)(qing)熱(re)(re)(re)墜痰(tan)(tan)，兩藥(yao)合(he)用(yong)，清(qing)(qing)(qing)(qing)(qing)熱(re)(re)(re)定(ding)驚(jing)化(hua)痰(tan)(tan)，共(gong)為(wei)(wei)君(jun)藥(yao)。三(san)黃(huang)(huang)清(qing)(qing)(qing)(qing)(qing)臟腑(fu)(fu)熱(re)(re)(re)，水(shui)牛角青(qing)黛清(qing)(qing)(qing)(qing)(qing)血(xue)分(fen)熱(re)(re)(re)。冰片、朱砂，清(qing)(qing)(qing)(qing)(qing)熱(re)(re)(re)開竅(qiao)(qiao)安(an)神。天(tian)竺黃(huang)(huang)除清(qing)(qing)(qing)(qing)(qing)肺中之(zhi)熱(re)(re)(re)痰(tan)(tan)外(wai)，還能(neng)(neng)清(qing)(qing)(qing)(qing)(qing)心平肝、使(shi)神志(zhi)能(neng)(neng)清(qing)(qing)(qing)(qing)(qing)，竹瀝(li)尚能(neng)(neng)治(zhi)痰(tan)(tan)在(zai)經(jing)絡四肢(zhi)皮里膜外(wai)，膽南星善祛腦(nao)竅(qiao)(qiao)風痰(tan)(tan)，石菖(chang)蒲(pu)能(neng)(neng)“開心孔，利九竅(qiao)(qiao)”。諸藥(yao)合(he)用(yong)共(gong)為(wei)(wei)臣(chen)藥(yao)。石菖(chang)蒲(pu)性(xing)溫，平衡眾(zhong)多苦寒藥(yao)物，且能(neng)(neng)化(hua)濕開胃、開竅(qiao)(qiao)豁(huo)痰(tan)(tan)、醒神益(yi)智，兼為(wei)(wei)佐(zuo)藥(yao)。郁金(jin)活血(xue)行氣推(tui)動諸藥(yao)到達病(bing)所，且能(neng)(neng)止(zhi)痛解(jie)郁、清(qing)(qing)(qing)(qing)(qing)心涼血(xue)、利膽退黃(huang)(huang)，為(wei)(wei)使(shi)藥(yao)。通過君(jun)臣(chen)佐(zuo)使(shi)的最佳組合(he)，珍黃(huang)(huang)安(an)宮片能(neng)(neng)清(qing)(qing)(qing)(qing)(qing)氣分(fen)血(xue)分(fen)及臟腑(fu)(fu)之(zhi)熱(re)(re)(re)，能(neng)(neng)祛心、肝、肺、腦(nao)、經(jing)路、四肢(zhi)及皮里膜外(wai)之(zhi)痰(tan)(tan)濕兼有活血(xue)行氣之(zhi)藥(yao)的助推(tui)，能(neng)(neng)開竅(qiao)(qiao)能(neng)(neng)透熱(re)(re)(re)，能(neng)(neng)鎮靜(jing)能(neng)(neng)安(an)神。故能(neng)(neng)治(zhi)療失眠屬(shu)實證者。